Automated Walk-Away Molecular Diagnostic System
This instrument, which automates a patented nucleic acid probe amplification technology for the detection of infectious diseases, was to be the first completely walk-away molecular diagnostic system of its kind. Early instrument prototypes were not functional, so the company turned to KMC Systems because of the project’s requirement of advanced engineering and manufacturing capabilities.
KMC Systems enhanced the customer’s design to improve reliability performance and software functionality. Because the system conducts automated functions, such as closed-tube sampling, reagent delivery, magnetic separation and washing, expertise in precision motion, software and fluidics was applied. Precision motion control and alignment were especially critical as the instrument was designed with a disposable that needed to be robotically moved in and out of various modules. The instrument also automates thermally controlled amplification and hybridization and chemiluminescence detection.
The manufacturable design was smoothly transitioned to KMC Systems’ production facility. KMC has continued to provide sustaining engineering support and implemented continuous reliability improvements, which have resulted in the most successful instrument of its type in the market.
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