Automated Immunoblot Analyzer
Creating tools to automate previously manual processes is a major trend in the medical and laboratory worlds. One company recognized a customer’s need for an automated solution to process immunoblot test strips for the confirmatory detection of HIV and HVC in blood. Due to the complexity of the engineering work required, the company contracted KMC Systems to design the instrument.
By applying expertise in software, electrical, systems and mechanical engineering, KMC Systems created an instrument that automated reagent delivery and mixing, strip washing and incubation, and CCD imaging and analysis. In particular, automating the assay process proved challenging. KMC Systems solved this by developing a disposable that contained the immunoblot strip. It also developed a multi-functional carousel that provided 37° C incubation, rocked the disposable to mix reagent, and had a centrifugal function to move spent reagent into a waste receptacle on the disposable. KMC also developed powerful and robust pattern recognition algorithms to interpret the results and rules for artifact rejection.
KMC Systems accounted for manufacturing during design and smoothly transitioned the project to production to speed time to market. The instrument was contract manufactured at KMC Systems’ Merrimack, NH, location.
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